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Impact of Adoption of Meld Score for Graft Allocation on Blood Components Transfusion during Olt |
Alexandre Teruya, M.D., Flavio Takaoka, M.D., Ph.D., Alexandre P. Oliveira, M.D., Marcel V. Vitoreli, M.D., Raffael C. Zamper, M.D. Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil |
INTRODUCTION: Blood components transfusion during orthotopic liver transplant (OLT) is related to surgical bleeding and coagulation impairment due to liver dysfunction. Despite a reduce on blood transfusion rates in the last years it still requires an important blood bank support. Since July of 2006 the Model for End Stage Liver Disease - MELD - score has been adopted to define graft allocation in our country. A recent article has demonstrated that patients with a MELD score grater than 30 have received more blood components durig OLT1. OBJECTIVE: Analyze the impact of the adoption of MELD score for graft allocation on blood components transfusion during OLT. METHODS: We retrospectively reviewed 456 OLTs - 413 before MELD era and compared the amount of blood components transfused to these groups. RESULTS: After the new organ allocation criteria, the average MELD score has raised from 19,4 to 28,6 . Average transfusion on both groups is shown is shown on table 1.[table1]CONCLUSION: Since adoption of MELD score as determinant of graft allocation, patients have been receiving larger amounts of red blood cells, fresh frozen plasma and cryoprecipitate. 1 - Xia, V, et al. Preoperative Characteristics and Intraoperative Transfusion and Vasopressor Requirements in Patients With Low Vs. High MELD Scores. Liver Transplantation 12:614-620, 2006. Anesthesiology 2008; 109 A507 |
Blood Component transfusion | RBC | FFP | Cryo | Platelets | | Pre-MELD | 2,05 | 2,46 | 0,14 | 0,44 | | Post-MELD | 3 | 4,07 | 0,24 | 0,34 | Average blood components transfusion. RBC - Red Blood Cells, FFP - Fresh frozen plasma, Cryo - Cryoprecipitate |