A507
October 19, 2008
9:00 AM - 11:00 AM
Room Hall E2-Area F,
Impact of Adoption of Meld Score for Graft Allocation on Blood Components Transfusion during Olt
Alexandre Teruya, M.D., Flavio Takaoka, M.D., Ph.D., Alexandre P. Oliveira, M.D., Marcel V. Vitoreli, M.D., Raffael C. Zamper, M.D.
Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil
INTRODUCTION: Blood components transfusion during orthotopic liver transplant (OLT) is related to surgical bleeding and coagulation impairment due to liver dysfunction. Despite a reduce on blood transfusion rates in the last years it still requires an important blood bank support. Since July of 2006 the Model for End Stage Liver Disease - MELD - score has been adopted to define graft allocation in our country. A recent article has demonstrated that patients with a MELD score grater than 30 have received more blood components durig OLT1.

OBJECTIVE: Analyze the impact of the adoption of MELD score for graft allocation on blood components transfusion during OLT.

METHODS: We retrospectively reviewed 456 OLTs - 413 before MELD era and compared the amount of blood components transfused to these groups.

RESULTS: After the new organ allocation criteria, the average MELD score has raised from 19,4 to 28,6 . Average transfusion on both groups is shown is shown on table 1.[table1]CONCLUSION: Since adoption of MELD score as determinant of graft allocation, patients have been receiving larger amounts of red blood cells, fresh frozen plasma and cryoprecipitate.

1 - Xia, V, et al. Preoperative Characteristics and Intraoperative Transfusion and Vasopressor Requirements in Patients With Low Vs. High MELD Scores. Liver Transplantation 12:614-620, 2006.

Anesthesiology 2008; 109 A507
Blood Component transfusion
RBCFFPCryoPlatelets
Pre-MELD2,052,460,140,44
Post-MELD34,070,240,34
Average blood components transfusion. RBC - Red Blood Cells, FFP - Fresh frozen plasma, Cryo - Cryoprecipitate

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