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October 19, 2009
2:00 PM - 4:00 PM
Room Area M
The Type of the Sense Against Stimuli Was Different in Gender
  **   Tomoko Fukada, M.D., Hiroko Iwakiri, M.D., Ikue Hoshi, M.D., Rika Nakayama, M.D., Makoto Ozaki, M.D.
Department of Anesthesiology, Tokyo Women's Medical University, School of Medicine, Tokyo, Japan
Introduction: Males are reported to have higher pain thresholds and therefore show higher tolerance to noxious stimulation than females. Pain Vision® PS-2100 (Nipro Co., Osaka, Japan) is a device that measures a magnitude of pain objectively by painless electrical stimulation; minimum perceived current (MPC), pain threshold (PT) and pain degree (PD). It evaluates human pain without relying on subjective criteria, like numerical rating scale (NRS). In this study, to confirm whether males complain less pain than females, we quantify the magnitude of pain when rods weighing on the right dorsal surface of the hand.

Methods: After obtaining IRB approval, 68 healthy volunteers (20-50yrs old, M: F =35: 33) were enrolled in this study.

MPC is defined as the minimum perceived current required to first sense a gradually increasing pulsed current (frequency is 50 Hz, and the pulse width is 0.3 ms) applied to the left medial forearm.

PT is defined as the compatible electrical current with which he/she feels the intensity of ongoing pain.

PD is calculated as (PT - MPC) / MPC× 100.

MPC, PT, and PD were evaluated when rods weighing 0, 200, 400, 200, and 0 g were placed (in those order) on the right dorsal surface of the hand. He/she was also asked to assess his/her pain subjectively as NRS when each rod was placed.

Results: The males' MPCs were higher than females' MPC at each rod weighing on the right dorsal surface of the hand; MPCs were unchanged regardless of any rods weighing. PTs, PDs, and NRSs were generally increased and decreased alone during the changes of rods; there were individual varieties, not gender differences in changes of PT and PD.[figure1][figure2]Conclusion: Multiple factors such as age, social factors, psychological reasons, culture influences, and previous memories were involved in pain. Moreover, we would like to indicate that the type of stimuli should be added to the factors of gender differences against pain because the only sense against MPC was blunt in males, not PT or PD.

From Proceedings of the 2009 Annual Meeting of the American Society Anesthesiologists.
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