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A3067
October 21, 2019
10/21/2019 9:30:00 AM - 10/21/2019 11:30:00 AM
Room WA2 - Area B
Dronabinol Use in Acute Pain Management for Chronic Marijuana Users
Sona Doshi, M.D.
University of Southern California, Los Angeles, Los Angeles, California , United States
Disclosures: S. Doshi: None.
Introduction:The analgesic benefit of cannabinoids has recently become a point of interest given the increase in recreational and medical use of marijuana. Cannabis has confirmed benefits in the oncology population, improving both appetite and pain control. Recently, synthetic cannabinoids have also been shown effective in enhancing pain control regimens in chronic pain populations. While the use of smoked marijuana has not been used in the perioperative setting due to its detrimental effects on respirations and healing, synthetic cannabinoids may have a role in improving perioperative pain control in chronic marijuana users. Case Report:The Acute Pain Service is consulted for postoperative pain control in patients undergoing painful surgery or those with a history of complex pain management. Post operatively, each patient is optimized with standard multimodal analgesia, which included a combination of neuraxial vs. peripheral nerve block, topical local anesthetics, oral/IV opioids, NMDA antagonists, NSAID’s, muscle relaxants, acetaminophen, and anticonvulsants. 3 patients however, with history of chronic CBD and/or THC use, complained of pain refractory to standard medication regimens, and were started on oral Dronabinol, which not only improved the patients pain, but also improved the effectiveness of their pain regimen.

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